Founded in 2000, CanAm Bioresearch is located in Winnipeg, Canada. CanAm Bioresearch is an established pharmaceutical contract research organization focused on pre-clinical drug discovery. CanAm Advantages: • Integrated CRO with flexible access to chemistry, biology and analytical • Company leadership has experience discovering NCEs now on the market • Highly competent and experienced research team - proven ability to deliver clinical candidates • Outstanding skills to tackle difficult chemistry and solve complex problems through an integrated multi-disciplinary approach • Customer focused: we operate as your own research team on your terms • Central time zone convenient for all of North America and Europe CanAm's clientele includes startup, small and large pharmaceutical companies, and academic institutions. Research contracts can range from simple chemical synthesis or single compound testing in our ADME and biological assays, to FTE-based full scale integrated discovery projects. We are experienced in protecting client confidentiality and intellectual property. Medicinal Chemistry and Custom Chemical Synthesis Solutions • Chemical synthesis of analogs • Chemical libraries based on our collections of capping groups • Rapid delivery, typically weekly • Experience in hit to lead generation and optimization • Difficult chemistry welcome! Analytical Chemistry Solutions • Pharmacokinetics experiments • Tissue distribution • Metabolite identification • Stability studies • Determination of chemical purity • Solubility studies Biological Solutions Assays include: • Biochemical • Electrophysiological • Metabolic stability • Cellular penetration FTE contracts: • Very competitive rates compared to US and Western Europe • Project leadership and medicinal chemistry guidance available Fee for service contracts: • Custom synthesis of any organic molecule • Up to 1 kg scale synthesis