We seek to discover new treatments for brain diseases by studying proven patterns of wellness and disease from indigenous people. Our findings show that chronic exposure to BMAA can trigger Alzheimer’s-like brain tangles and amyloid deposits. As far as we are aware, this is the first time researchers have been able to successfully replicate brain tangles and amyloid deposits in an animal model through exposure to an environmental toxin. We have only one wish at the Institute for Ethnomedicine: to discover new treatments for serious illnesses. This focus has led to the discovery of two promising new drugs for ALS, Alzheimer’s, Parkinson’s and other tangle diseases. We have a third drug in development. Our novel path to discovery has been exciting. Each step of this path, beginning in Guam, has brought us closer to a cure.