PAI is a Boston-based health-economics and outcomes-research consultancy that has been providing strategic advice, technical support, and contract research services for over 40 years to numerous clients in the pharmaceutical, biotechnology, medical-device, and diagnostics industries throughout North America, Europe, and Asia. Our core competencies include economic modeling, database analyses, value justification & technology assessments, and patient-reported outcomes. PAI has authored more than 250 articles in major peer-reviewed journals, including JAMA, Cancer, Archives of Internal Medicine, Journal of Clinical Oncology, American Journal of Cardiology, Stroke, Diabetes Care, Thrombosis Research, Journal of Pediatrics, Vaccine, American Journal of Public Health, Quality of Life Research, and others.