Simple phenomena + clinical need + real-world constraints As bioengineers, we seek to apply scientific understanding to develop technology for improving human health. Our work is defined by the manipulation of simple physical and biochemical phenomena to create devices for unmet clinical needs, and attention to real-world constraints improves the chances that our work will impact patients. The interplay between science, technology, clinical need, and real-world constraints creates a puzzle that requires a disciplined form of creativity and invention.