Addressing Unmet Medical Need Catalytic Impact Foundation's mission is to accelerate innovation in life sciences and healthcare, funding companies that address significant unmet medical need. Using the tools of traditional venture capital, we invest philanthropic capital to support companies developing transformative, life-sustaining technologies. Bridging the Valley of Death Capital for early-stage companies can be difficult to obtain. There is often a funding gap between research grants and for-profit investment. Philanthropic capital can help bridge that gap, the so-called “valley of death,” moving much-needed innovations along the development path to FDA approval so they are available to patients everywhere. Our focus is championing extraordinary innovation, catalytic ideas, and visionary leaders in six verticals: Children's Health, Women's Health, Brain & Mental Health, Rare Disease, Aging, and Health Equity. Regenerative Philanthropy Every donation to Catalytic Impact Foundation becomes an investment. CIF's investment in a promising treatment de-risks the opportunity and catalyzes more institutional investment, further accelerating the treatment on its path to commercialization. When we are successful, our fund grows, our portfolio of investments grows, and more patients access the cures they need to live healthier, longer lives. Catalytic Impact Foundation is a registered 501(c)(3) charitable organization incorporated in New York State (formerly named Cavendish Impact Foundation).