Fever syndromes account for over 1 billion episodes annually and are one of the most common reasons to seek care worldwide. For the nearly 3 billion people who live in the equatorial belt a high fever can signal the onset of potentially deadly infectious diseases. E25Bio Inc. is a Tough Tech company backed by Venture Capital (Khosla Ventures, MIT The Engine) and NIH/Gates Foundation developing Rapid Diagnostic Tests for fever infectious diseases. Existing solutions rely heavily on centralized laboratory equipment and trained staff, cold chain for specimen transport, and hub-and-spoke reporting mechanisms for data. Our innovations aim to provide people with a much simpler alternative: to identify infectious diseases in time to avoid serious complications and death. Through early and accurate screening, we can help equip the right patient with the right treatment at the right time.