Forsyth is the world’s leading independent nonprofit research institute dedicated to improving oral health, and reducing interrelated systemic diseases and conditions. The Forsyth Institute portfolio includes basic, translational and clinical research, community-benefit programs for underserved populations and Forsyth Faculty Associates, a private dental practice serving Kendall Square and surrounding areas. The Forsyth Institute reinvents oral and overall health through pioneering biomedical research and transformational healthcare practices. Forsyth uses its unique knowledge of oral medicine to elucidate new biomedical insights, and to find the best ways to help people live healthier lives. Over 110 years ago, The Forsyth Institute was founded to provide badly needed dental care to disadvantaged children in Boston. In the following decades, Forsyth’s research changed the way the world understands oral health. Forsyth scientists have demonstrated links between oral diseases and health challenges like heart disease, diabetes, and even certain cancers, and are tackling other global infectious diseases like TB and HIV/AIDS. Key areas of investigation include: • Oral-Systemic Disease Connections • Global Infectious Diseases • Molecular Microbiology and Genetics • Immunology • Skeletal Biology/Biomineralization • Development Biology and Regenerative Medicine