The Ophthalmic Research Institute of Australia trading as Australian Vision Research is a not-for-profit organisation dedicated to promoting and supporting research and awareness into the causes of eye disease and the prevention of blindness. The Institute was founded in 1953 by a group of ophthalmologists concerned with the need to advance eye research in Australia. Since then, the organisation has distributed millions of dollars to fund research that has changed practice and advanced basic knowledge. We report the outcomes of all the research we support and promote best practice ophthalmic medical care. In 2020 the Ophthalmic Research Institute of Australia, following a strategic review, relaunched as Australian Vision Research. Our name has changed, however our mandate to support important research has not. Australian Vision Research has a wide focus on supporting research into all major eye diseases, as opposed to focusing on a single eye disease. Research grants are made available annually through Australian Vision Research’s available funds, which are sourced through bequests and donations from individuals and organisations. A large proportion of these funds have been donated by people whose sight has been saved as a result of advances in eye care, and who wish to express their appreciation in a tangible way.